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GLP-1 Side Chains
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Peptide Intermediates
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Fmoc-His-Aib-OH
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Fmoc-Ile-Aib-OH
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Fmoc-Tyr(tBu)-Aib-OH
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Fmoc-Glu(OtBu)-Aib-OH
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Fmoc-His(Fmoc)-Aib-OH
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Fmoc-His(Fmoc)-Aib-OSu
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Tirzepatide Fragments
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CAS:2682040-93-1
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CAS:3034670-52-2
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CAS:1262308-37-1
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CAS:2461524-68-3
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CAS:2656383-24-1
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CAS:2656383-25-2
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API & Excipients
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Cosmetic Peptides
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Oligopeptide-1
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NonaPeptide-1
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Copper Tripeptide-1
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Acetyl Hexapeptide-8
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Palmitoyl Tripeptide-1
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Decarboxy Carnosine HCl
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Active Ingredients
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New patent, new ingredient | Congen Crystal High-Gloss Ring Peptide, creating a translucent crystal skin
Publish Time:
2025-07-29
Radiant, hydrated, and crystal-like... these keywords have swept the global beauty market, representing the common pursuit of ideal skin among consumers.
Recently, CongenPharma's independently developed Decanoyl cyclotetrapeptide has been granted a Chinese patent , patent number: ZL202510235238.0. This innovative ingredient, hailed as the "crystal highlight cyclopeptide," provides a new scientific solution for creating "luminous crystal skin".

Is it the scientific answer to radiant skin?
1. Stable
→ The cyclic structure resists enzymatic degradation, resulting in longer-lasting activity.
2. Mild and effective
→ The safe concentration is 4 times that of linear peptides, suitable for sensitive skin;
→ The cyclic structure more easily binds to receptor sites, enabling precise action;
→ Better transdermal penetration, easier absorption by the skin.
Triple highlight engine, creating "crystal skin"
→ Even and luminous: Increases α-crystallin, reduces the accumulation of damaged proteins, making skin translucent like crystal;
→ Strengthens the barrier: Promotes the production of filaggrin, resulting in a dense, damage-resistant stratum corneum, presenting healthy beauty;
→ Hydrated and plump: Upregulates hyaluronic acid, providing excellent water retention, making skin soft and radiant.

Comparative experiment: Cyclotetrapeptide outperforms linear peptide
Reduced cytotoxicity, safe concentration is 4 times that of linear peptide
Linear tetrapeptides show significant cytotoxicity at 80μM, with relative cell activity dropping to approximately 55%. The cyclized tetrapeptide shows significantly reduced cytotoxicity, with no significant cytotoxicity at 80μM, demonstrating good biosafety.

α-Crystallin increased by 2.06 times
Using hydrogen peroxide to stimulate human epidermal cells (HaCaT) to create a model, the experiment shows that Decanoyl cyclotetrapeptide enhances α-crystallin expression 2.06 times more effectively than Palmitoyl tetrapeptide-10.

Filaggrin increased by 2.53 times, hyaluronic acid increased by 4.22 times

5 scenarios, unlock "crystal skin" with one click
Daily skincare: "Apply-on hydro-boosting serum", radiant glow
Emergency rescue for fatigue: Rescues dullness caused by staying up late, overtime, and fatigue
Brightening for sensitive skin: Mild and effective, precisely targets inflammation and pigmentation
Post-sun care: Counteracts the accumulation of damaged proteins, strengthens the barrier
Synergistic youthfulness: Hydrated and plump, fine lines are invisible

Innovative raw materials, collaborative application
Contact us to obtain detailed product information:marketing@congenpharm.com
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