Amino-PEG2-acetic Acid CAS 134978-97-5 | PEG Linker | CongenPharma
Publish Time:
2026-09-10
Amino-PEG2-acetic Acid, also known as 2-(2-(2-Aminoethoxy)ethoxy)acetic acid, is a bifunctional PEG linker and peptide synthesis building block containing both a primary amino group and a carboxylic acid group.
With a molecular weight of 163.17 g/mol, this short-chain PEG linker combines two reactive functional groups with a hydrophilic PEG2 spacer, making it useful for peptide modification, bioconjugation, PNA and nucleic acid probe development, molecular probe research, and drug discovery.
Product Information
| Property | Details |
|---|---|
| Product Name | Amino-PEG2-acetic Acid |
| CAS No. | 134978-97-5 |
| Chemical Name | 2-(2-(2-Aminoethoxy)ethoxy)acetic acid |
| Alternative Name | Amino-PEG2-acetic Acid |
| Molecular Formula | C₆H₁₃NO₄ |
| Molecular Weight | 163.17 g/mol |
| Product Type | Bifunctional PEG Linker / Peptide Building Block |
| Factory | Guangzhou Congen Pharmatec Co.,Ltd. |
What Is Amino-PEG2-acetic Acid?
Amino-PEG2-acetic Acid is a heterobifunctional PEG linker with an amino group at one end and a carboxylic acid group at the other.
The two functional groups provide convenient sites for further chemical conjugation, while the PEG2 spacer contributes hydrophilicity and molecular flexibility.
This combination makes Amino-PEG2-acetic Acid a versatile building block for connecting or modifying different molecules in pharmaceutical and biotechnology research.
Key Features
1. Bifunctional PEG Linker
The molecule contains both amine (-NH₂) and carboxylic acid (-COOH) functional groups, enabling different conjugation strategies and subsequent molecular modification.
2. Hydrophilic PEG2 Spacer
The short PEG2 chain provides a hydrophilic and flexible spacer between functional groups. This can help improve molecular accessibility and provide suitable spacing in conjugation systems.
3. Peptide Synthesis Building Block
Amino-PEG2-acetic Acid can be used as a building block for peptide modification and peptide conjugation research, particularly where a short PEG spacer is required.
4. Suitable for Bioconjugation Research
Its two reactive groups make it useful for connecting peptides, proteins, small molecules and other functional molecules in bioconjugation and drug discovery research.
Applications of Amino-PEG2-acetic Acid
Amino-PEG2-acetic Acid is mainly used in pharmaceutical research, biotechnology and chemical biology.
Peptide Modification and Conjugation
Amino-PEG2-acetic Acid can serve as a linker or spacer in the development of modified peptides and peptide conjugates.
Potential applications include:
- Peptide modification
- Peptide conjugates
- Functional peptide development
- Peptide-based molecular probes
- Peptide drug discovery research
Bioconjugation
The amino and carboxylic acid groups provide reactive sites for conjugation with different molecular components.
It can therefore be considered for research involving:
- Peptide–small molecule conjugates
- Protein conjugation
- Molecular probes
- Targeted conjugation systems
- Drug delivery research
PNA and Nucleic Acid Research
Amino-PEG2-acetic Acid can also be used as a linker or functional building block in PNA and nucleic-acid-related research, including the development of molecular probes and detection systems.
Drug Discovery and Chemical Biology
The combination of a short PEG spacer and two functional groups makes this compound useful in drug discovery, chemical biology and molecular engineering where controlled molecular conjugation is required.
Why Choose Amino-PEG2-acetic Acid from CongenPharma?
CongenPharma supplies Amino-PEG2-acetic Acid (CAS 134978-97-5) for pharmaceutical, peptide and biotechnology research applications.
We focus on high-quality peptide and pharmaceutical building blocks, supported by controlled manufacturing processes and quality management systems.
Our capabilities can support customers from R&D and laboratory-scale requirements to larger-scale procurement, subject to product specifications and project requirements.
For detailed specifications, COA, SDS/MSDS, analytical data, sample availability and bulk quotation, please contact the CongenPharma team.
Frequently Asked Questions
What is Amino-PEG2-acetic Acid?
Amino-PEG2-acetic Acid is a bifunctional PEG linker containing an amino group and a carboxylic acid group. It is commonly used as a building block for peptide modification, bioconjugation and related research.
What is the CAS number of Amino-PEG2-acetic Acid?
The CAS number of Amino-PEG2-acetic Acid is 134978-97-5.
What is Amino-PEG2-acetic Acid used for?
It is used in peptide synthesis and modification, bioconjugation, PNA/nucleic acid probe development, molecular probe research and drug discovery.
What is the molecular weight of Amino-PEG2-acetic Acid?
The molecular weight of Amino-PEG2-acetic Acid is 163.17 g/mol.
Is Amino-PEG2-acetic Acid a PEG linker?
Yes. Amino-PEG2-acetic Acid is a short-chain bifunctional PEG linker, featuring a PEG2 spacer together with amino and carboxylic acid functional groups.
Related Keywords
Amino-PEG2-acetic Acid | CAS 134978-97-5 | 2-(2-(2-Aminoethoxy)ethoxy)acetic acid | Amino PEG linker | PEG2 linker | bifunctional PEG linker | peptide linker | peptide building block | bioconjugation linker | peptide modification | PNA linker | nucleic acid probe | drug discovery building block
Applications: Peptide Synthesis | Peptide Modification | Bioconjugation | PNA Research | Nucleic Acid Probes | Molecular Probes | Drug Discovery | Chemical Biology | Targeted Delivery Research
