Compared to anti-dandruff agents, how does hexamidine compare to ZPT and OCT in terms of its advantages?
Publish Time:
2025-10-15
Compared to ZPT and another commonly used anti-dandruff ingredient, OCT (piroctone olamine), hexamidine demonstrates significant advantages across key dimensions such as efficacy, application, safety, and mildness, offering a superior solution for dandruff relief.
Targeting the culprit behind dandruff, Malassezia—Guanidinium Its minimum inhibitory concentration (MIC) is 12.5 μg/mL, and the minimum microbicidal concentration (MMC) is 100 μg/mL. Notably, due to its cationic nature and the resulting adsorption onto hair, it effectively enhances and prolongs its anti-dandruff action—a feature that other anti-dandruff agents lack. *
In addition to removing dandruff, hexamidine also offers multiple advantages. *：
① Convenient and easy to use: water-soluble, non-settling, and无需悬浮;
② Does not cause discoloration;
③ Extremely safe and gentle, even non-irritating to the eyes, and can also remain on the skin and scalp;
④ Broader application scope: In addition to traditional anti-dandruff shampoos, it can also be used in transparent shampoos, hair care products, and spray formulations, among others;
⑤ Will not affect the reduction or change in the shampoo's texture, and long-term use will not impact hair quality.
Additionally, the Cosmetic Ingredient Review (CIR) panel in the United States concluded that use at concentrations of 0.10% or lower is safe.
